Ingenia Therapeutics is about to be the first foreign biotech to list in South Korea's Kosdaq in five years.

Ingenia Therapeutics is about to be the first foreign biotech to list in South Korea's Kosdaq in five years.

Key points

  • Ingenia Therapeutics, a Boston biotech, is about to become the first foreign biotech to list on the Kosdaq in five years, with retail subscription July 30-31 and listing August 4.
  • Its lead drug was licensed for about 1 trillion won in 2022, then its partner was bought by Merck for up to 3 billion dollars in 2024.
  • Three more Korean-founded, US-based biotechs are lining up behind it, each carrying its own big pharma licensing deal.
  • Korea's financial regulator says one NYSE-listed company has directly asked about a Kosdaq listing too, ahead of a Korea Premium Week investor event September 28 to October 16 and a separate Silicon Valley push planned later this year.

This month, SK Hynix pulled off the largest American depositary receipt offering in Wall Street history, raising 26.5 billion dollars on the Nasdaq and pricing its shares above the Seoul price, something I wrote about here when it happened. Money and attention flowed out of Korea and into New York. Now Korea's own exchange wants to run that trade in reverse, and it already has a real company doing it, not just a plan.

A Boston biotech opens the door

Ingenia Therapeutics, a drug developer founded in Boston in 2018, opens retail subscription for its Kosdaq listing on July 30 and 31, with shares set to begin trading August 4. It will be the first foreign biotech to list on the Kosdaq in five years, since Neoimmunetech, a Maryland company, listed there in March 2021. That five year wait says something about how rare this still is. Ingenia is going public through a Korean Depositary Receipt, or KDR, a structure that lets a foreign company keep its shares parked with an overseas custodian while a Korean depositary issues a matching security that trades on the Kosdaq, so Korean retail investors can buy in without opening a foreign brokerage account.

Ingenia has a real reason to believe Korean investors will show up. Its lead antibody candidate, IGT-427, was licensed to the UK biotech EyeBio in 2022 for close to 1 trillion won. Two years later, in 2024, EyeBio itself was bought by Merck (MRK), the American pharmaceutical giant known outside the US as MSD, for 3 billion dollars, and IGT-427 became one of MSD's core eye disease programs, now in two Phase 3 trials under the code name MK-8748 for wet age-related macular degeneration. MSD is expected to start an additional Phase 3 trial for diabetic eye swelling later this year. None of that revenue belongs to Ingenia anymore, since it licensed the drug away years ago, but the deal is the proof point the company is selling to Korean investors: a molecule discovered in its own labs is now inside a major pharmaceutical company's late stage pipeline. Ingenia's offering is priced between 12,000 and 14,500 won a share, aiming to raise 60 to 72.5 billion won, led by Samsung Securities.

It is not the only one

Three more Korean-founded, US-based biotechs are reportedly moving toward the same Kosdaq path, each with its own licensing deal to point to. Breeze Bio signed a 970 billion won immune modulation deal with Genentech, a Roche subsidiary, in 2024. Pinetree Therapeutics licensed a targeted protein degradation program to AstraZeneca for about 820 billion won. Kaigene signed a deal worth up to 744 million dollars with Celltrion, a Korean drugmaker, for two autoimmune disease antibody programs. All four companies share the same basic story: founded or led by Korean scientists, headquartered in the United States, and now looking to raise money from the Korean public markets that first funded the research behind them, using the same KDR structure since US corporate law does not fit neatly into how Korean securities rules are written.

Regulators want more of this, not less

This is not a coincidence limited to biotech. Korea's Financial Services Commission told the president this month that one company listed on the New York Stock Exchange has directly asked the Korea Exchange about a Kosdaq listing, and about ten more foreign companies are reviewing the idea. The regulator would not name the NYSE company. To go after more of them, the government is running what it calls Korea Premium Week from September 28 through October 16, an investor relations push aimed at global pension funds, investment banks, and asset managers, with a separate push into Silicon Valley planned for later this year specifically to recruit growth companies to list on the Kosdaq.

The timing lines up with a broader rework of the Kosdaq itself. Regulators are running what they call a three part structural overhaul: easier listing standards for innovative companies (three new qualifying categories added for the second half of this year), tougher delisting rules for weak ones (already in effect since July 1), and a new tiered market segment structure starting in January 2027 that is meant to separate stronger companies from the rest. Settlement is also set to move from two days to one day by 2027. None of this guarantees the ten companies the regulator mentioned actually list, and Ingenia's own offering still has to clear its subscription this month before any of it means much. But the direction is clear: after watching SK Hynix's money and headlines go to New York, Korea is trying to build a path for capital to flow back the other way.

Sources

Figures in this piece are sourced from Korean financial media and public IPO filings. This is not investment advice.

Frequently asked questions

What is Ingenia Therapeutics, and why is its Kosdaq listing unusual?

Ingenia Therapeutics is a drug developer founded in Boston in 2018. It is going public on South Korea's Kosdaq exchange through a Korean Depositary Receipt, and will be the first foreign biotech to list there in five years, since Neoimmunetech in March 2021.

What is a Korean Depositary Receipt (KDR)?

A KDR lets a foreign company keep its shares held with an overseas custodian while a Korean depositary issues a matching security that trades on a Korean exchange, so Korean retail investors can buy in without opening a foreign brokerage account.

What deal is Ingenia Therapeutics pointing to in its IPO pitch?

Ingenia licensed its lead antibody candidate, IGT-427, to the UK biotech EyeBio in 2022 for close to 1 trillion won. EyeBio was then bought by Merck (MRK) for 3 billion dollars in 2024, and the drug is now in two Phase 3 trials under the name MK-8748.

Are other foreign companies planning to list on the Kosdaq?

Yes. Three more Korean-founded, US-based biotechs, Breeze Bio, Pinetree Therapeutics, and Kaigene, are reportedly moving toward Kosdaq listings, and Korea's Financial Services Commission says a company listed on the NYSE has directly inquired about a listing too, with roughly ten more foreign companies reviewing the idea.

What is Korea Premium Week?

It is a government investor relations event running September 28 through October 16, 2026, aimed at global pension funds, investment banks, and asset managers, meant to pitch Korea's capital markets to foreign investors and companies as regulators also overhaul Kosdaq listing and delisting standards.

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Mia Park
Mia Park

Mia Park was born and raised in Korea and covers its markets and business news for AIStockWire, from the Kospi and Kosdaq to Samsung, SK Hynix, and the companies shaping the country's technology sector. She got her start writing for a Korean entertainment blog, a long way from stock filings, but has always enjoyed knowing what is happening back home before everyone else does.